Table 2.
Plasma biochemical parameters from animals fed STD and treated with either OEA or POEA (10 mg/kg) for 15 days.
| Standard Diet (STD) | |||
|---|---|---|---|
| Plasma Metabolites | VEH | OEA | POEA |
| Glucose (mg/dL) | 164.00 ± 8.45 | 168.57 ± 4.50 | 160.33 ± 12.37 |
| Triglycerides (mg/dL) | 150.29 ± 12.27 | 161.20 ± 8.82 | 136.33 ± 7.93 |
| Cholesterol (mg/dL) | 68.83 ± 4.80 | 48.29 ± 3.76 * | 69.83 ± 7.42 |
| VLDL (mg/dL) | 27.67 ± 1.30 | 30.06 ± 2.45 | 32.24 ± 1.76 |
| LDL (mg/dL) | 77.90 ± 7.55 | 72.06 ± 7.67 | 87.43 ± 7.47 |
| HDL (mg/dL) | 10.57 ± 1.70 | 19.90 ± 1.34 * | 23.60 ± 6.09 |
| Uric acid (mg/dL) | 2.28 ± 0.34 | 1.40 ± 0.22 | 1.97 ± 0.36 |
| Urea (mg/dL) | 16.86 ± 1.40 | 14.00 ± 1.29 | 13.40 ± 1.14 |
| Creatinine (mg/dL) | 0.75 ± 0.09 | 1.00 ± 0.19 | 0.53 ± 0.15 |
| Bilirubin (mg/dL) | 0.18 ± 0.02 | 0.19 ± 0.02 | 0.10 ± 0.00 * |
| AST (UI) | 150.57 ± 19.91 | 138.00 ± 27.06 | 160.67 ± 24.25 |
| ALT (UI) | 53.14 ± 9.66 | 69.67 ± 11.14 | 58.40 ± 11.71 |
Plasma biochemical parameters in standard diet (STD) group treated chronically over 15 days with N-acylethanolamines NAEs; oleoylethanolamide (OEA) and palmitoleylethanolamide (POEA). Data are expressed as means ± standard error of the mean (SEM) (n = 8 animals/group) analyzed by two-way ANOVA (diet and treatment) and Bonferroni post hoc test. (*) p < 0.05 significant differences compared with vehicle (VEH) group. VLDL; Very-low-density lipoprotein, LDL; low-density lipoprotein, HDL; hight-density lipoprotein, AST; aspartate aminotransferase, and ALT; alanine aminotransferase.