Table 2.

Transcription factors from the global network for RA with at least one differentially expressed gene overlapping from the analysis of (a) responders/non-responders RA patients to anti-TNF treatment (37 and 41 RA patients treated with adalimumab and etanercept, respectively) and (b) after/before anti-TNF treatment of RA patients (two different cohorts of 40 and 36 RA patients from baseline and after three months treatment with Infliximab or Adalimumab). ↓ denotes downregulation.

Source	TF	Responders/Non-Responders	After Treatment/Before Treatment
CoRegNet and RA map	NFKBIA	↓	↓
	JUN		↓
	FOS	↓	↓
CoRegNet	TNFAIP3		↓
	BCL6	↓
	MXD1	↓
	MNDA	↓
	DAZAP2	↓
	FOSB		↓
	NFKBIA	↓	↓
	JUN		↓