Table 2.
Reactome pathway analysis of individual functional protein partners correlated with the three SOX genes.
| #Term ID | Term Description | False Discovery Rate |
|---|---|---|
| HSA-201681 | TCF-dependent signaling in response to WNT | 4.69 × 10−15 |
| HSA-3769402 | Deactivation of the β-catenin transactivating complex | 4.69 × 10−15 |
| HSA-8878159 | Transcriptional regulation by RUNX3 | 1.63 × 10−12 |
| HSA-212436 | Generic Transcription Pathway | 3.64 × 10−12 |
| HSA-2990846 | SUMOylation | 5.69 × 10−12 |
| HSA-74160 | Gene expression (Transcription) | 9.40 × 10−12 |
| HSA-195253 | Degradation of β-catenin by the destruction complex | 1.42 × 10−11 |
| HSA-162582 | Signal Transduction | 3.63 × 10−11 |
| HSA-1640170 | Cell Cycle | 4.88 × 10−11 |
| HSA-201722 | Formation of the β-catenin/TCF transactivating complex | 7.06 × 10−11 |
| HSA-6804760 | Regulation of TP53 activity through methylation | 4.81 × 10−10 |
| HSA-3065678 | SUMO is transferred from E1 to E2 (UBE2I, UBC9) | 6.14 × 10−10 |
| HSA-4411364 | Binding of TCF/LEF: CTNNB1 to target gene promoters | 1.59 × 10−9 |
| HSA-8951430 | RUNX3 regulates WNT signaling | 1.59 × 10−9 |
| HSA-3108232 | SUMO E3 ligases SUMOylate target proteins | 1.86 × 10−9 |
| HSA-69563 | p53-dependent G1 DNA Damage Response | 3.53 × 10−9 |
| HSA-1643685 | Disease | 4.70 × 10−9 |
| HSA-3700989 | Transcriptional Regulation by TP53 | 6.39 × 10−9 |
| HSA-5663202 | Diseases of signal transduction | 6.39 × 10−9 |
| HSA-6804757 | Regulation of TP53 Degradation | 6.39 × 10−9 |