Figure 3.

(A) Results from P. perfoliatus extract on carrageenan-induced leukocyte migration into the peritoneal cavity in mice (total number × 10⁶). Animals received the extract (200, 400 and 600 mg/kg, p.o.), diclofenac (20 mg/kg, p.o.) or vehicle 1 h before carrageenan injection (500 µg, i.p.). (B) Results from P. perfoliatus extract on acetic acid-induced vascular permeability. Mice received different treatments 1 h before acetic acid (0.6%, i.p.) and Evans blue dye injections. The amount of dye extravasation into the abdominal cavity was quantified and used as an indicator of inflammation degree. The results are shown as means ± SEM (n = 5–6). * p < 0.05 compared to saline group. ^# p < 0.05 compared to control (carrageenan or acetic acid only treated group).