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. 2021 Aug 10;26(16):4826. doi: 10.3390/molecules26164826

Figure 4.

Figure 4

Analgesic activities of P. perfoliatus extract. (A) Acetic acid-induced writhing assay. Mice were treated either with the extract (200 and 400 mg/kg, p.o.) or diclofenac (20 mg/kg, p.o.) 1 h prior to the acetic acid (0.7%, 1 mL/100 g) injection. (B) Hot plate response latency (s) assay. (C) AUC of response latency shown in panel (B). The data results were quantified at one-hour intervals after administration of either the extract (200 and 400 mg/kg, p.o.) or nalbuphine (10 mg/kg, p.o.). Results are shown as mean ± S.E.M (n = 5–8). * p < 0.05 vs. control values.