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. 2021 Aug 10;26(16):4826. doi: 10.3390/molecules26164826

Table 3.

Results from P. perfoliatus extract on Brewer’s yeast-induced pyrexia in mice.

Sample Dose (mg/kg) Rectal Temperature (°C) Rectal Temperature Recorded Following Different Treatments (h)
0.5 1 2 3 24
Control - 38.78 ± 0.26 38.88 ± 0.16 38.66 ± 0.19 38.86 ± 0.19 38.70 ± 0.20 38.34 ± 0.21
P. perfoliatus extract 200 37.94 ± 0.36 38.24 ± 0.13 38.84 ± 0.46 38.62 ± 0.21 38.28 ± 0.24 37.26 ± 0.63
400 38.86 ± 0.33 39.10 ± 0.32 38.96 ± 0.27 38.52 ± 0.15 38.74 ± 0.16 37.84 ± 0.45
600 38.56 ± 0.15 38.73 ± 0.14 37.40 ± 0.20 * 37.5 ± 0.4 * 37.30 ± 0.17 * 37.50 ± 0.24
Paracetamol 150 38.60 ± 0.18 38.14 ± 0.19 37.50 ± 0.31 37.12 ± 0.29 * 36.96 ± 0.24 * 36.50 ± 0.22 *

Results are shown as mean ± S.E.M (n = 5), * p < 0.05 vs. control values. 18 h after yeast injection.