Table 2.
General features of MRSA O20 and D2 clinical strains. PathogenFinder 1.1, ResFinder 2.1 (90% identity and 40% minimum length) and PlasmidFinder 1.3 (<98% homology) were used to estimate the number of pathogenicity determinants, genes and plasmids, respectively, within the genome. ISsaga: Semi-Automatic Insertion Sequences Annotation.
| O20 | D2 | ||
|---|---|---|---|
| MLST | ST22 (CC22) | ST105 (CC5) | |
| SCCmec | SCCmec type IV(2B) | SCCmec type II(2A) | |
| spa typing | t6966 | t535 | |
| agr typing | agr IV | agr II | |
| Antimicrobial resistance genes |
erm(C), blaZ, mecA gyrA (S85P) |
erm(A)-type, aadD-type, ant(9)-Ia, blaZ, mecA-type gyrA (S84L), grlA (S80Y), grlA (E84G) |
|
| Virulence | Adherence | bbp, ebp, eno, fnbA, icaACDR, srtB | bbp, ebp, eno, fnbA, icaABCDR, sdrE, srtB |
| Exoenzymes | adsA, aur, chp, geh, lip, sak, sspABC | adsA, aur, chp, geh, lip, sak, sspABC | |
| Host Immune Evasion | cap8, sbi, scn | cap8A, sbi, scn | |
| Iron uptake and metabolism | isdABCDEFG | isdABCDEFG | |
| Toxins and secretion machinery | cidA, esaAB, essAB, esxA, hlb, hld, hlgABC, hly/hla, hysA, pvl, sec, seg, sei, sel, sem, sen, seo | cidA, esaABDEG1G9, essABC, esxABCD, hlb, hld, hlgABC, hly/hla, hysA, lukD, pvl, sed | |
| Plasmid type | repL (rep10) | repA_N (rep20), rep1-type (rep22) | |
| Pathogen (Probability of being a human pathogen) | 97.8% | 98.3% | |
| ISsaga | 15 ORFs related to IS(s) were found in these replicons: 5 Putative complete ORFs 6 Putative partial ORFs 4 Uncategorized ORFs |
11 ORFs related to IS(s) were found in these replicons: 4 Putative complete ORFs 5 Putative partial ORFs 2 Uncategorized ORFs |
|