Table 3.

Bidirectional permeability measured in Caco-2 cells. Data are mean values of duplicates from standard permeability assays. Final concentration of compounds in donor compartment was 1 µM.

Compound	Caco-2
	Papp,AB (10−6 cm/s)	PappBA (10−6 cm/s)	Efflux
Cyclosporin	7.2	26.4	3.7
Emodepside	8.8	36	4.1
BI-1	<0.53	<0.23	n.c.
BI-2	BLQ	BLQ	n.c.
BI-3	<1.2	0.65	n.c.
BI-4	<0.036	<0.014	n.c.

n.c.: Not calculated.