Figure 5.

Correlation between the concentrations of immune indicators and abundance of fecal microbiota. The correlated module was analyzed using a weighted gene co-expression network analysis (WGCNA). Correlation networks were generated using Spearman’s rank correlation coefficients and visualized using the Cytoscape. (A) The heatmap of the WGCNA module. (B) Correlation network among immunoglobulins, cytokines, and 89 interacting OTUs in MEpink module. Strong correlations between OTUs and immune index (|R| ≥ 0.5 and p < 0.05) are displayed in the network in the red edge.