Table A1.
SE, SP, PPV, and NPV of GLIM using different combinations of phenotypic criteria and etiologic criteria in diagnosing malnutrition compared with PG-SGA.
| Combination | SE (%,95%CI) |
SP (%,95%CI) |
PPV (%,95%CI) |
NPV (%,95%CI) |
κ |
|---|---|---|---|---|---|
| Weight loss Reduced intake or assimilation |
48.5 (42.1–55.0) | 98.2 (95.9–99.2) | 95.1 (89.2–98.0) | 72.1 (67.7–76.2) | 0.488 |
| Low BMI Reduced intake or assimilation |
10.2 (6.8,15.0) | 99.7 (98.0–100.0) | 96.0 (77.7–99.8) | 60.7 (56.4–64.8) | 0.113 |
| MMR * Reduced intake or assimilation |
36.2 (30.1–42.7) | 99.4 (97.6–99.9) | 97.7 (91.2–99.6) | 68.4 (64.0–72.5) | 0.390 |
| Any phenotypic criterion Reduced intake or assimilation |
60.4 (53.8–66.7) | 98.2 (95.8–99.2) | 95.9 (91.0–98.3) | 77.5 (73.1–81.4) | 0.618 |
| Weight loss Disease burden/inflammation |
0 (0–2.0) | 99.7 (98.0–100.0) | 0 (0–94.5) | 58.1 (53.9–62.2) | −0.004 |
| Low BMI Disease burden/inflammation |
0 (0–2.0) | 100.0 (98.6–100.0) | - | - | 0.000 |
| MMR * Disease burden/inflammation |
0 (0–2.0) | 100.0 (98.6–100.0) | - | - | 0.000 |
| Any phenotypic criterion Disease burden/inflammation |
0 (0–2.0) | 99.7 (98.0–100.0) | 0 (0–94.5) | 58.1 (53.9–62.2) | −0.004 |
| Weight loss Any etiologic criterion |
47.2 (40.7–53.8) | 97.9 (95.4–99.1) | 94.1 (87.8–97.4) | 72.1 (67.6–76.1) | 0.485 |
| Low BMI Any etiologic criterion |
10.2 (6.8–15.0) | 99.7 (98.0–100.0) | 96.0 (77.7–99.8) | 60.7 (56.4–64.8) | 0.113 |
| MMR * Any etiologic criterion |
36.2 (30.1–42.7) | 99.4 (97.6–99.9) | 97.7 (91.2–99.6) | 68.4 (64.0–72.5) | 0.39 |
| Any phenotypic criterion Any etiologic criterion |
60.4 (53.8–66.7) | 97.9 (95.4–99.1) | 95.3 (90.2–97.9) | 77.5 (73.1–81.4) | 0.614 |
SE: sensitivity; SP: specificity; PPV: positive predictive value; NPV: negative predictive value; CI: confidence interval; PG-SGA: Patient-generated Subjective Global Assessment; BMI: body mass index; MMR: muscle mass reduction. * MMR in this table was defined by the combination of CC, FFMI, or ASMI.