Table 2.
Entry | Base | Yield 2 | Entry | Base | Yield 2 |
---|---|---|---|---|---|
1 | - | 14 | 6 | K2CO3 | 54 |
2 | LiOH·H2O | 60 | 7 | Cs2CO3 | 69 |
3 | NaOH | 65 | 8 | KOt Bu | 69 |
4 | KOH | 75 | 9 | K3PO4 | 60 |
5 | CsOH·H2O | 91 | 10 | CsF | 39 |
1 Reaction conditions: 1a (0.20 mmol), AuPd–Fe3O4 (1.4 mol%), base (3.0 equiv), O2 (1.0 atm), methanol (1.0 mL), r. t., 18 h. 2 Determined from 1H NMR spectral analysis through the use of mesitylene as an internal standard.