Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
PAb421 influences p53 exonuclease and sequence-specific DNA binding activities in opposite manners. Metal affinity-purified full-length p53 was incubated with increasing amounts of PAb421 and tested for exonuclease activity (A, lanes 2 to 7) or sequence-specific DNA binding (B). p53 was also incubated with a non-p53-specific antibody (PAb108, specific for SV40 T-Ag) and tested for exonuclease activity (A, lanes 8 to 13).
