Table 1.
Characteristics and bone parameters according to tertiles of estimated phytate intake (mg/day).
| Low IP6 Intake | Moderate IP6 Intake | High IP6 Intake | p-Value | |
|---|---|---|---|---|
| (0–199) mg/Day | (200–325) mg/Day | >325 mg/Day | ||
| (n = 145) | (n = 127) | (n = 147) | ||
| Anthropometric parameters | ||||
| Age (years) | 56.6 ± 3.1 | 55.4 ± 2.7 a | 55.0 ± 2.4 a | <0.001 |
| BMI (kg/cm2) | 25.5 ± 4.2 | 25.5 ± 4.9 | 24.2 ± 3.7 a,b | 0.011 |
| Hip circumference (cm) | 106 ± 12 | 106 ± 13 | 102 ± 13 a | 0.019 |
| Waist Circumference (cm) | 89 ± 15 | 89 ± 15 | 86 ± 15 | 0.144 |
| Body Fat Mass (%) | 34.6 ± 9.1 | 34.2 ± 9.5 | 31.7 ± 9.5 a | 0.018 |
| Systolic Blood Pressure (mmHg) | 118 ± 15 | 120 ± 15 | 119 ± 15 | 0.468 |
| Diastolic Blood Pressure (mmHg) | 75 ± 10 | 75 ± 10 | 73 ± 11 | 0.140 |
| Dietary parameters | ||||
| Estimated Phytate Intake (mg/day) | 117 ± 54 | 268 ± 37 a | 499 ± 129 a,b | 0.032 |
| MedDiet Score (14-points) | 8.2 ± 1.6 | 8.9 ± 1.5 a | 9.7 ± 1.9 a,b | <0.001 |
| High Adherence to Med Diet (≥9 points) | 64 (44.1%) | 81 (65.9%) a | 108 (73.5%) a | <0.001 |
| Lumbar Spine L1–L4 | ||||
| Bone Mineral Density (g/cm2) | 0.69 ± 0.07 | 0.75 ± 0.07 a | 0.87 ± 0.09 a,b | <0.001 |
| t-score | −1.70 ± 0.44 | −1.31 ± 0.50 a | −0.44 ± 0.72 a,b | <0.001 |
| Low-BMD (t-score ≤ −1) | 132 (91.0%) | 92 (74.8%) a | 30 (20.4%) a,b | <0.001 |
Values are expressed as mean ± SD or frequency (percentage). p-value was calculated with ANOVA test and Bonferroni as a post-hoc test (quantitative data); or chi-square test (qualitative data). Statistics: a p < 0.05 versus corresponding value of low IP6 intake group; b corresponding value of moderate IP6 intake group. IP6:Myo-inositol hexaphosphate (phytate; IP6).