Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2021 Jul 31;13(8):1188. doi: 10.3390/pharmaceutics13081188

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2021 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

PMC Copyright notice

Concentration versus time curves and calculated pharmacokinetic parameters of nanocrystal dispersion (F5) and suspension (S5) in (a) plasma, (b) brain, (c) liver, and (d) kidney after oral administration in rats (n = 3 per time point) at a dose of 10 mg/kg, in fasted and fed state (C_max—maximum concentration, t_max—time of maximum concentration, t_1/2—terminal elimination half-life, AUC_0-_∞—area under the concentration versus time curve). Terminal elimination half-life in the brain was not calculated due to erratic concentration-time profiles.