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. 2021 Jul 31;13(8):1188. doi: 10.3390/pharmaceutics13081188

Table 3.

Particle size (z-ave), polydispersity index (PDI), and zeta potential (ZP) of nanocrystal dispersions after one hour of milling (mean ± SD, n = 3).

Formulation Milling Media Volume (%, v/v) z-Ave (nm) PDI ZP (mV)
60 195.8 ± 1.7 0.238 ± 0.029
F1 40 236.7 ± 1.9 0.208 ± 0.002 −17.5 ± 1.6
20 233.6 ± 2.7 0.260 ± 0.007
F2 60 137.7 ± 2.2 0.226 ± 0.015
40 165.5 ± 4.3 0.226 ± 0.011 −16.8 ± 0.5
20 229.9 ± 4.9 0.205 ± 0.012
F3 60 235.1 ± 4.2 0.273 ± 0.044
40 239.3 ± 3.3 0.251 ± 0.017 −28.0 ± 1.2
20 298.6 ± 9.1 0.301 ± 0.019
F4 60 155.6 ± 2.3 0.258 ± 0.040
40 176.0 ± 3.1 0.250 ± 0.040 −19.2 ± 0.7
20 233.1 ± 6.2 0.277 ± 0.016
F5 60 148.7 ± 2.5 0.231 ± 0.010
40 174.1 ± 0.6 0.231 ± 0.015 −21.8 ± 5.6
20 222.8 ± 3.3 0.253 ± 0.021
F6 60 138.7 ± 2.3 0.225 ± 0.011
40 153.1 ± 1.8 0.197 ± 0.021 −31.9 ± 1.8
20 185.3 ± 1.5 0.179 ± 0.012
F7 60 151.6 ± 4.3 0.206 ± 0.012
40 170.2 ± 2.4 0.220 ± 0.008 −36.8 ± 1.1
20 214.2 ± 5.5 0.205 ± 0.022
F8 60 143.6 ± 1.4 0.231 ± 0.006
40 160.4 ± 3.1 0.208 ± 0.014 −38.1 ± 1.9
20 182.7 ± 1.2 0.202 ± 0.011