Skip to main content
. 2021 Aug 19;13(8):1293. doi: 10.3390/pharmaceutics13081293

Table 1.

1H NMR chemical shifts in δ and Δδ of LVF protons in free state and LVF/SBE-β-CD 1:1 complex (10 mM in D2O); for multiplet, doublet, or AB system, the reported δ and Δδ refer to the centered signal.

Protons LVF LVF/SBE-β-CD Δδ *
CH3 1.32 (d) 1.41 +0.09
N-CH3 2.78 (s) 2.74 −0.04
(CH2)2-N-CH3 3.24 (m) 3.19 −0.05
(CH2)2-N 3.38 (s) 3.43 +0.05
2 4.29 (AB system) 4.36 +0.07
3 4.47 (d) 4.54 +0.07
8 7.28 (m) 7.47 +0.19
5 8.22 (d) 8.30 +0.08

* Δδ = δcomplex − δfree.