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. 2021 Aug 19;13(8):1293. doi: 10.3390/pharmaceutics13081293

Table 3.

Hydrodynamic radius (RH), polydispersity index (PDI), and zeta potential (ζ) of CH NPs loading LVF.

NPs Sample * RH ± S.D. (nm) PDI % ζ ± S.D. (mV)
Empty CH/TPP 92 ± 43 21 +25.8 ± 3.9
LVF–CH/TPP2 85 ± 32 20 +28.0 ± 3.5
LVF–CH/TPP3 86 ± 37 20 +26.4 ± 4.6
Empty CH/SBE-β-CD 134 ± 41 17 +21.8 ± 5.2
LVF–CH/SBE-β-CD2 165 ± 49 20 +25.0 ± 2.2
LVF–CH/SBE-β-CD3 159 ± 52 20 +24.2 ± 4.2

* The amount of CH is always 10 mg. The amount of polyanion is 3 mg for TPP and 7.5 mg for SBE-β-CD. The number as subscript of NPs acronyms indicates the theoretical amount of LVF in mg (2 mg or 3 mg). LVF was added to CH solutions for the preparation of CH/TPP NPs and to SBE-β-CD for the preparation of CH/SBE-β-CD NPs. The final volume was maintained at 8 mL for all formulations.