Extended Data Fig. 6 ∣. DEGs in the brains of individuals with COVID-19 show no significant overlap with brain PMI-sensitive genes.

a, Comparison of post-mortem interval (PMI)-sensitive genes (left column, from a previous publication²⁷) and COVID-19 DEGs (all other columns). No statistically significant overlap is observed (Fisher’s exact test). b, The previous study²⁷ categorized PMI-sensitive genes in two categories: glial genes upregulated and neural genes downregulated. Minimal overlap is seen with COVID-19 changes of the same category (for example, glial genes upregulated in COVID-19 versus glial genes upregulated with extended PMI). c, Heat map showing that PMI-sensitive genes are not the DEGs in COVID-19 and thus not driving the DEG-based findings of our study.