Table 5.
The changes of hepatic lipid profiles in SD rats fed different experimental diets for 6 and 11 weeks.
| Diet | C | CS | DM | DM + TZD | DM + CS |
|---|---|---|---|---|---|
| 6 weeks | |||||
| Total cholesterol (mg/g liver) | 53.7 ± 11.4 | 34.5 ± 5.2 * | 59.5 ± 15.2 | 45.0 ± 10.7 # | 35.9 ± 9.9 # |
| Triglyceride (mg/g liver) | 45.4 ± 11.4 | 35.6 ± 6.2 | 59.4 ± 18.2 | 42.8 ± 12.4 | 43.7 ± 12.1 |
| 11 weeks | |||||
| Total cholesterol (mg/g liver) | 89.5 ± 24.8 | 57.1 ± 12.7 * | 116.4 ± 15.7 * | 101.2 ± 12.2 | 45.8 ± 13.2 #@ |
| Triglyceride (mg/g liver) | 63.5 ± 12.3 | 58.5 ± 9.5 | 79.4 ± 23.8 | 52.5 ± 13.4 # | 71.7 ± 17.5 |
Results are expressed as mean ± SD for each group (n = 8). The significant difference (p < 0.05) was analyzed by one-way ANOVA and two-tailed Student’s t-test. *: versus C; #: versus DM; @: versus DM + TZD. C: control diet; CS: control diet + 5% high molecular weight chitosan; DM: diabetes + control diet; DM + TZD: diabetes + control diet +0.8 mg/kg thiazolidinediones (rosiglitazone); DM + CS: diabetes + control diet + 5% high molecular weight chitosan.