Table 4.
Diagnostic performance of each type in the NICE clasification stratified by polyp size
| Type of classification | Sensitivity (%) (95% CI) | Specificity (%) (95% CI) | PPV (%) (95% CI) | NPV (%) (95% CI) | Accuracy (%) (95% CI) |
|---|---|---|---|---|---|
| Type 1 | |||||
| < 10 mm | 81.2 (63.6–92.8) | 99.4 (97.9–99.9) | 92.9 (76.5–99.1) | 98.2 (96.2–99.3) | 97.8 (95.8–99.1) |
| ≥ 10 mm | 100.0 (61.5–100.0) | 100.0 (96.5–100.0) | 100.0 (61.5–100.0) | 100.0 (96.5–100.0) | 100.0 (96.7–100.0) |
| All size | 86.0 (72.1–94.7) | 99.6 (98.5–100.0) | 94.9 (82.7–99.4) | 98.8 (97.4–99.6) | 98.5 (97.1–99.4) |
| Type 2 | |||||
| < 10 mm | 99.1 (97.4–99.8) | 82.4 (65.5–93.2) | 98.2 (96.2–99.3) | 90.3 (74.2–98.0) | 97.6 (95.4–98.9) |
| ≥ 10 mm | 99.3 (96.2–100.0) | 90.0 (68.3–98.8) | 98.6 (95.2–99.8) | 94.7 (74.0–99.9) | 98.2 (94.8–99.6) |
| All size | 99.2 (97.9–99.8) | 85.2 (72.9–93.4) | 98.3 (96.8–99.3) | 92.0 (80.8–97.8) | 97.8 (96.1–98.8) |
| Type 3 | |||||
| < 10 mm | 100.0 (9.4–100.0) | 99.7 (98.5–100.0) | 66.7 (9.4–99.2) | 100.0 (98.5–100.0) | 99.7 (98.5–100.0) |
| ≥ 10 mm | 77.8 (40.0–97.2) | 99.4 (96.5–100.0) | 87.5 (47.3–99.7) | 98.7 (95.5–99.8) | 98.2 (94.8–99.6) |
| All size | 81.8 (48.2–97.7) | 99.6 (98.6–100.0) | 81.8 (48.2–97.7) | 99.6 (98.6–100.0) | 99.3 (98.1–99.8) |
| Determination of neoplastic polyp (Type 2/3) | |||||
| < 10 mm | 99.4 (97.9–99.9) | 81.2 (63.6–92.8) | 98.2 (96.2–99.3) | 92.9 (76.5–99.1) | 97.8 (95.8–99.1) |
| ≥ 10 mm | 100.0 (96.5–100.0) | 100.0 (61.5–100.0) | 100.0 96.5–100.0) | 100.0 (61.5–100.0) | 100.0 (96.7–100.0) |
| All size | 99.6 (98.5–100.0) | 86.0 (72.1–94.7) | 98.8 (97.4–99.6) | 94.9 (82.7–99.4) | 98.5 (97.1–99.4) |
The sensitivity, specificity, PPV, NPV, and accuracy of each type do not differ significantly between polyp sized < 10 mm and ≥ 10 mm
NICE classification narrow-band imaging international colorectal endoscopic classification, CI confidence interval, PPV positive predictive value, NPV negative predictive value