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(A) Schematic illustration of the engineering EcN strain named SYNB1891; (B) Tumor inhibition and (C) survival rates of SYNB1891 treatment in B16F10 tumor-bearing mice. Reproduced with permission from Jose M. Lora, Nature Communications; published by Springer Nature, 2020. ** p = 0.0058 (blue stars), **** p < 0.0001 (pink stars), ** p = 0.0078 (pink stars), ** p = 0.006 (black stars), *** p = 0.0004–0.0006 (black stars).
