Table 2.
Multivariate Cox regression for 30-day mortality and ICU admission.
| Variable | HR | 95% CI | p-Value |
|---|---|---|---|
| 30 days mortality | |||
| Age | 1.09 | [1.06–1.12] | <0.001 |
| CCI | 0.98 | [0.84–1.14] | 0.78 |
| Severe immunosuppression | 5.87 | [0.87–1.03] | 0.01 |
| Days since onset of symptoms | 0.95 | [0.87–1.03] | 0.20 |
| WHO ordinal scale at admission | 1.21 | [1.02–1.43] | 0.04 |
| CRP levels (mg/mL) | 1.02 | [1–1.04] | 0.03 |
| Positive PUA | 0.53 | [0.22–1.28] | 0.16 |
| ICU admission | |||
| CCI | 0.85 | [0.73–0.99] | 0.05 |
| Antibiotic treatment before hospitalization (atb = 1) | 2.2 | [1.12–4.35] | 0.03 |
| Antibiotic treatment before hospitalization (atb = 2) | 3.67 | [1.06–12.75] | 0.05 |
| PCTI levels (ng/mL) | 1.04 | [1.01–1.07] | 0.01 |
| Positive PUA | 0.8 | [0.25–2.54] | 0.70 |
Note. Abbreviations: HR, Hazard Ratio; CI, Confidence Interval; CCI, Charlson comorbidity index; CRP, C-reactive protein; atb, antibiotic; PCTI, procalcitonin; PUA, pneumococcal urinary antigen.