Table 1.
Patients’ characteristics.
| Characteristics | SLE–Non-LN | LN | Control | p Significance |
|---|---|---|---|---|
| Number of patients | 44 | 38 | 40 | 0.47 |
| Women:Men ratio | 2/1 | 2/1 | 2/1 | 0.89 |
| Age (years) | 42.6 ± 6.3 | 44.8 ± 5.5 | 43.7 ± 6.2 | 0.56 |
| Disease duration (years) | 6.4 ± 1.3 | 6.7 ± 1.1 | − | 0.28 |
| SLEDAI | 6.2 ± 4.7 | 7.4 ± 5.3 | − | 0.35 |
| dsDNA (IU/mL) | 320.1 ± 122.4 | 342.7 ± 98.2 | 80.2 ± 16.2 | 0.02 |
| BMI (Kg/mp) | 22.9 ± 1.7 | 23.0 ± 2.1 | 22.0 ± 3.3 | 0.64 |
| Leucocytes (cells/mmc) | 3800 ± 2008 | 4050 ± 1040 | 5860 ± 1070 | 0.03 |
| Haemoglobin (g/L) | 10.3 ± 1.1 | 10.8 ±0.8 | 12.8 ± 1.2 | 0.02 |
| Phosphorus (mg/dL) | 3.6 ± 0.7 | 3.6 ± 0.9 | 3.7 ± 0.6 | 0.41 |
| Calcium (mg/dL) | 9.11 ± 0.4 | 9.18 ± 0.6 | 9.22 ± 0.57 | 0.28 |
| LDH (U/L) | 297 ± 65 | 307 ± 63 | 316 ± 57 | 0.08 |
| Glycemia (mg/dL) | 84.1 ± 11.3 | 78.7 ± 13.7 | 82.7 ± 11.4 | 0.11 |
| ASAT (U/L) | 19.4 ± 11.2 | 17.2 ± 8.4 | 19.2 ± 8.7 | 0.24 |
| ALAT (U/L) | 17.1 ± 13.2 | 16.2 ± 6.2 | 20.2 ± 10.3 | 0.08 |
| Cholesterol (mg/dL) | 152.5 ± 21.2 | 146.2 ± 24.1 | 142.5 ± 19.9 | 0.07 |
| Triglycerides (mg/dL) | 89.5 ± 12.7 | 81.4 ± 10.5 | 86.7 ± 15.5 | 0.23 |
| Albumin (g/dL) | 3.26 ± 0.25 | 3.68 ± 0.34 | 4.01 ± 0.44 | <0.04 |
| Urea (mg/dL) | 35.4 ± 11.4 | 34.6 ± 0.7 | 30.2 ± 0.9 | 0.08 |
| Creatinine (mg/dL) | 1.0 ± 0.22 | 1.28 ± 0.11 | 0.77 ± 0.12 | 0.02 |
| eGFR (mL/min/1.73 mp) | 91.45 ± 12.23 | 82.17 ± 17.12 | 97.82 ± 7.22 | 0.02 |
| Uric acid (mg/dL) | 4.2 ± 1.3 | 3.8 ± 1.0 | 4.2 ± 1.2 | 0.13 |
| UACR (mg/g creatinine) | 10.81 ± 3.88 | 19.84 ± 2.97 | 7.34 ± 0.22 | 0.03 |
| Haematuria (sw-RBC/camp) | 5 ± 4 | 16 ± 7 | 3 ± 1 | 0.02 |
| Leucocyturia (sw-leuc/camp) | 5.3 ± 1.1 | 6.8 ± 0.9 | 3.8 ± 2.7 | 0.07 |
| Urinary b2-microglobulin (mg/L) | 0.22 ± 0.07 | 0.38 ± 0.14 | 0.12 ± 0.04 | 0.04 |
| ESR (mm/h) | 21.7 ± 17.1 | 24.5 ± 11.0 | 5.7 ± 5.0 | 0.02 |
| CRP (mg/dL) | 1.04 ± 0.72 | 1.29 ± 0.35 | 0.14 ± 0.12 | 0.02 |
| C3 (mg/dL) | 82.4 ± 21.2 | 70.5 ± 15.8 | 98.5 ± 25.1 | 0.03 |
| C4 (mg/dL) | 10.2 ± 1.7 | 7.4 ± 1.3 | 19.4 ± 9.3 | 0.01 |
| C1q (mg/dL) | 4.22 ± 0.95 | 3.02 ± 1.1 | 15.4 ± 6.3 | 0.04 |
SLEDAI—Systemic Lupus Erythematosus Disease Activity Index, BMI—body mass index; LDH—lactatdehydrogenase; ASAT—aspartate aminotransferase; ALAT—alanyl aminotransferase; eGFR—estimated glomerular filtration rate; UACR—urinary albumin: creatinine ratio; ESR—erythrocyte sedimentation rate; CRP—C reactive protein; p—statistical significance.