Figure 5.

Cranberry extract inhibits CCHFV infection. Vero cells were treated for 1 h with extract at increasing concentrations (0, 3.125, 6.25, 12.5, 25, 50, and 100 μg/mL) during infection (CoT) with CCHFV at an MOI of 0.05 FFU/cell. Then, the virus inoculum was removed, and at 24 h p.i., the viral infectivity rate was determined by IFA. The virus infectivity was expressed as a % of the positive control of infection (untreated, set at the 100% value). Data represent mean ± SD of three independent experiments performed in triplicate.