Table 4.
Inoculations of ZIKV into adult male guinea pigs (GP).
| Animal ID | ZIKV Strain | Inoculation Route | Sex |
|---|---|---|---|
| Guinea Pig 1 | Zika PRVACB59 | SC | Male |
| Guinea Pig 2 | Zika PRVACB59 | SC | Male |
| Guinea Pig 3 | Zika PRVACB59 | SC | Male |
| Guinea Pig 4 | Mock | SC | Male |
| Guinea Pig 5 | Zika PRVACB59 | MB | Male |
| Guinea Pig 6 | Zika PRVACB59 | MB | Male |
| Guinea Pig 7 | Zika PRVACB59 | MB | Male |
| Guinea Pig 8 | Mock | MB | Male |
All animals were euthanized at 7 dpi. SC = subcutaneous, MB = mosquito bite. SC inoculated animals were subcutaneously inoculated with 2.6 × 106 PFU in 100 µL of virus. Mock animals were negative controls and inoculated with 100 µL of PBS or fed on by non-infectious mosquitoes.