Table 4.
Behavioural measures of emotional processing at baseline and on-drug. Values represent means with standard deviations in parentheses.
| Placebo | Pramipexole | |||
|---|---|---|---|---|
| Baseline | On-Drug | Baseline | On-Drug | |
| Facial expression recognition task (FERT) | ||||
| Hit rate (%) | ||||
| Anger | 55.6 (10.5) | 59.3 (7.7) | 53.3 (12.7) | 57.9 (14.3) |
| Disgust | 66.9 (9.6) | 67.5 (12.6) | 62.3 (15.8) | 62.1 (17.5) |
| Fear | 54.6 (15.2) | 61.1 (10.2) | 49.4 (17.2) | 55.6 (16.2) |
| Happiness | 80.3 (5.4) | 78.2 (5.3) | 77.2 (7.3) | 74.8 (5.5) |
| Sadness | 63.5 (8.5) | 65.1 (9.3) | 63.2 (12.5) | 61.2 (12.3) |
| Surprise | 68.9 (6.5) | 74.2 (5.5) | 67.4 (8.3) | 72.6 (6.8) |
| Neutral | 83.3 (12.4) | 90.6 (10.0) | 87.6 (12.6) | 87.6 (17.6) |
| False alarm rate (%) | ||||
| Anger | 1.7 (1.1) | 1.8 (1.9) | 1.7 (1.9) | 2.1 (2.1) |
| Disgust | 2.4 (1.7) | 1.9 (1.4) | 2.5 (2.0) | 2.2 (1.7) |
| Fear | 1.3 (0.9) | 1.2 (0.9) | 0.9 (1.2) | 1.2 (1.2) |
| Happiness | 0.5 (0.8) | 0.6 (0.8) | 0.5 (0.7) | 0.7 (0.8) |
| Sadness | 3.0 (2.4) | 2.8 (2.4) | 3.5 (3.3) | 3.5 (2.7) |
| Surprise | 2.5 (1.9) | 1.6 (1.4) | 3.4 (2.5) | 2.0 (2.1) |
| Non-identification rate (%) | ||||
| Anger | 33.8 (7.0) | 32.8 (8.3) | 35.6 (9.4) | 34.3 (11.3) |
| Disgust | 21.7 (5.2) | 18.2 (7.4) | 24.3 (7.2) | 22.1 (8.5) |
| Fear | 23.2 (2.5) | 22.5 (4.5) | 23.8 (6.1) | 22.4 (5.1) |
| Happiness | 16.8 (5.5) | 18.6 (5.2) | 19.3 (5.9) | 21.0 (4.8) |
| Sadness | 32.6 (7.7) | 31.8 (8.9) | 34.3 (11.9) | 35.0 (10.8) |
| Surprise | 25.8 (4.9) | 21.0 (5.3) | 27.0 (4.7) | 23.5 (4.1) |
| Reaction time (ms) | ||||
| Anger | 1429.6 (279.2) | 1356.6 (231.3) | 1396.9 (348.1) | 1274.1 (202.4) |
| Disgust | 1435.8 (247.4) | 1246.1 (194.0) | 1437.1 (307.3) | 1245.3 (165.6) |
| Fear | 1645.4 (325.7) | 1456.9 (314.7) | 1646.9 (446.1) | 1443.8 (316.5) |
| Emotional categorisation task (ECAT) | ||||
| Reaction time (ms) | ||||
| Positive | 724.9 (97.3) | 802.4 (120.0) | 748.0 (147.5) | 771.1 (126.1) |
| Negative | 835.3 (135.0) | 869.3 (153.9) | 799.0 (138.6) | 823.0 (171.1) |
| Faces dot probe task (FDOT) | ||||
| Vigilance bias score (ms) | ||||
| Masked positive | −7.7 (38.4) | −11.0 (54.1) | 8.1 (33.0) | 9.5 (37.5) |
| Masked negative | −3.4 (43.8) | −2.9 (32.1) | −16.1 (40.5) | −8.0 (28.1) |
| Unmasked positive | −4.9 (40.5) | 4.9 (35.6) | 4.0 (34.3) | −1.3 (40.3) |
| Unmasked negative | −0.1 (46.0) | −10.7 (33.7) | −12.0 (40.0) | −2.4 (31.3) |
| Emotional recall task (EREC) | ||||
| Hits (n correct) | ||||
| Positive | 4.4 (1.2) | 5.6 (2.7) | 5.6 (2.5) | 6.4 (3.2) |
| Negative | 3.5 (1.0) | 3.2 (2.1) | 4.0 (2.3) | 4.2 (2.2) |
| Intrusions (n wrong) | ||||
| Positive | 3.2 (2.8) | 7.9 (3.2) | 2.4 (2.7) | 8.9 (3.8) |
| Negative | 1.5 (1.6) | 4.4 (2.2) | 1.4 (1.7) | 5.1 (2.1) |