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. 2021 Jul 22;13(8):1118. doi: 10.3390/pharmaceutics13081118

Figure 5.

Figure 5

Mole fraction solubility of theobromine determined in water-free natural deep eutectic solvents at 25 °C. All designed solvents were prepared in unimolar proportions. For comparison, the solubilities in neat DMSO and 1:1 dioxane-water mixture were highlighted.