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Ketogenesis pathway in hepatic mitochondria. Low amounts of insulin and high amounts of glucagon in our blood stream trigger the augmentation of free fatty acids (FFAs), and increase uptake of FFAs into the mitochondria. Acetyl CoA is generated from beta-oxidation of Acyl CoA, which derives from FFAs. The production of ketones (acetoacetate, acetone, β-HB) in the liver is then increased.
