Table 4.
The effect of berberine on CVD risk factors and testosterone using a GEE model *.
| Outcomes | Beta | 95% CI | p |
|---|---|---|---|
| Total cholesterol (mmol/L) | −0.39 | −0.62, −0.16 | 0.001 |
| LDL-cholesterol (mmol/L) | −0.23 | −0.43, −0.02 | 0.03 |
| Triglycerides (mmol/L) | −0.31 | −0.67, 0.06 | 0.10 |
| HDL-cholesterol (mmol/L) | −0.03 | −0.09, 0.02 | 0.26 |
| SBP (mmHg) | −0.91 | −4.75, 2.93 | 0.64 |
| DBP (mmHg) | −0.31 | −3.42, 2.80 | 0.84 |
| BMI | −0.39 | −0.99, 0.21 | 0.20 |
| WHR | −0.006 | −0.02, 0.01 | 0.36 |
| Thromboxane A2 (pg/mL) | 8.46 | −23.0, 39.9 | 0.60 |
| Testosterone (nmol/L) | 1.31 | 0.30, 2.33 | 0.01 |
* GEE model incorporates changes at 8 and 12 weeks. A GEE model with an exchangeable correlation structure was used.