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In-vitro cytotoxicity (RCV, %) of CDDP-loaded (γ-Fe2O3/PLGA)/CS NPs (black column) and free CDDP (light grey column) in human lung adenocarcinoma A-549 cells, after 72 h of exposure to a wide range of NP concentrations (up to 20 μg/mL equivalent CDDP concentration). The statistical Student’s t-test, considering 95% confidence interval, was significant (* p < 0.05) or very significant (** p < 0.01, *** p < 0.001), compared with the free CDDP-treated group.
