Table 2.
Laboratory characteristics of participants (mean ± standard deviation).
| Variables | Control Group | Group I | Group II | p-Value |
|---|---|---|---|---|
| Hemoglobin (g/dL) | ||||
| Day 0 | 13.9 ± 2.2 | 14.2 ± 1.9 | 14.4 ± 2.1 | 0.797 |
| Day 2 | 13.3 ± 1.8 | 13.8 ± 2.5 | 14.1 ± 1.9 | 0.474 |
| Day 7 | 13.6 ± 1.8 | 13.9 ± 2.1 | 14.2 ± 2.3 | 0.657 |
| White blood cells (×109/L) | ||||
| Day 0 | 15.8 ± 4.1 | 14.1 ± 3.9 | 16.5 ± 4.2 | 0.215 |
| Day 2 | 17.3 ± 4.3 | 16.1 ± 3.2 | 18.4 ± 4.8 | 0.254 |
| Day 7 | 10.1 ± 2.1 | 9.7 ± 2.5 | 10.3 ± 3.2 | 0.786 |
| Lymphocyte (×109/L) | ||||
| Day 0 | 0.9 ± 0.4 | 0.7 ± 0.3 | 1.1 ± 0.3 | 0.005 |
| Day 2 | 1.5 ± 0.5 | 1.3 ± 0.4 | 1.8 ± 0.4 | 0.003 |
| Day 7 | 2.2 ± 0.3 | 1.9 ± 0.5 | 2.4 ± 0.5 | 0.002 |
| Neutrophil (×109/L) | ||||
| Day 0 | 13.4 ± 2.2 | 12.9 ± 2.4 | 14.1 ± 2.3 | 0.311 |
| Day 2 | 14.7 ± 2.7 | 13.5 ± 2.1 | 15.2 ± 2.9 | 0.139 |
| Day 7 | 8.6 ± 1.5 | 8.2 ± 1.7 | 8.8 ± 1.5 | 0.58 |
| Platelet (×109/L) | ||||
| Day 0 | 213.6 ± 20.5 | 206.8 ± 21.5 | 222.2 ± 99.7 | 0.744 |
| Day 2 | 244.5 ± 24.5 | 234.5 ± 21.1 | 246.2 ± 99.5 | 0.822 |
| Day 7 | 228.7 ± 21.5 | 216.3 ± 23.4 | 242.2 ± 91.8 | 0.392 |
| Albumin (g/dL) | ||||
| Day 0 | 3.7 ± 0.5 | 3.4 ± 0.4 | 3.9 ± 0.2 | 0.006 |
| Day 2 | 4.1 ± 0.3 | 3.9 ± 0.3 | 4.2 ± 0.3 | 0.014 |
| Day 7 | 4.3 ± 0.6 | 4.1 ± 0.5 | 4.4 ± 0.3 | 0.22 |
| Total bilirubin (mg/dL) | ||||
| Day 0 | 0.98 ± 0.1 | 0.92 ± 04 | 1.01 ± 0.2 | 0.559 |
| Day 2 | 0.91 ± 0.1 | 0.89 ± 0.1 | 0.95 ± 0.3 | 0.592 |
| Day 7 | 0.84 ± 0.2 | 0.88 ± 0.3 | 0.93 ± 0.1 | 0.334 |
| Alanine aminotransferase (IU/L) | ||||
| Day 0 | 39.7 ± 2.3 | 38.6 ± 2.8 | 40.2 ± 2.9 | 0.163 |
| Day 2 | 41.3 ± 2.9 | 40.5 ± 3.5 | 42.3 ± 3.1 | 0.208 |
| Day 7 | 37.5 ± 3.1 | 36.8 ± 3.2 | 38.1 ± 3.4 | 0.454 |
| Aspartate aminotransferase (IU/L) | ||||
| Day 0 | 37.1 ± 2.9 | 36.4 ± 3.5 | 38.5 ± 3.1 | 0.139 |
| Day 2 | 39.6 ± 2.3 | 38.3 ± 2.8 | 40.1 ± 2.9 | 0.103 |
| Day 7 | 33.2 ± 3.1 | 34.1 ± 3.2 | 32.8 ± 3.4 | 0.456 |
| Prothrombin time (seconds) | ||||
| Day 0 | 13.3 ± 1.1 | 13.1 ± 0.8 | 13.5 ± 1.5 | 0.536 |
| Day 2 | 13.7 ± 0.9 | 13.5 ± 1.2 | 13.9 ± 1.4 | 0.484 |
| Day 7 | 12.9 ± 0.5 | 13.3 ± 0.9 | 12.8 ± 1.5 | 0.044 |
| Partial thromboplastin time (seconds) | ||||
| Day 0 | 31.3 ± 3.1 | 30.4 ± 2.8 | 31.3 ± 2.4 | 0.577 |
| Day 2 | 32.5 ± 2.9 | 31.7 ± 2.2 | 31.7 ± 2.5 | 0.575 |
| Day 7 | 30.8 ± 2.5 | 31.1 ± 2.9 | 29.7 ± 2.3 | 0.23 |
| Serum urea (mg/dL) | ||||
| Day 0 | 48.4 ± 10.3 | 45.8 ± 11.8 | 51.3 ± 11.9 | 0.243 |
| Day 2 | 52.5 ± 11.9 | 47.2 ± 10.5 | 60.4 ± 10.1 | 0.002 |
| Day 7 | 34.7 ± 9.1 | 39.6 ± 12.2 | 37.6 ± 12.4 | 0.444 |
| Serum creatinine (mg/dL) | ||||
| Day 0 | 0.9 ± 0.2 | 0.8 ± 0.2 | 1.1 ± 0.2 | 0.000 |
| Day 2 | 1.1 ± 0.1 | 0.9 ± 0.1 | 1.2 ± 0.1 | 0.000 |
| Day 7 | 0.7 ± 0.3 | 0.7 ± 0.3 | 0.8 ± 0.3 | 0.349 |
| C-reactive protein (mg/L) | ||||
| Day 0 | 10.2 ± 1.2 | 9.8 ± 1.4 | 10.4 ± 1.3 | 0.368 |
| Day 2 | 14.3 ± 1.7 | 12.4 ± 1.1 | 12.9 ± 1.9 | 0.003 |
| Day 7 | 12.8 ± 1.1 | 11.7 ± 1.1 | 10.6 ± 1.1 | 0.000 |
| Ferritin (ng/mL) | ||||
| Day 0 | 488.9 ± 83.6 | 443.1 ± 110.3 | 501.1 ± 101.8 | 0.195 |
| Day 2 | 516.3 ± 90.2 | 524.6 ± 100.6 | 531 ± 95.1 | 0.898 |
| Day 7 | 306.3 ± 71.6 | 323 ± 90.3 | 341.5 ± 80.7 | 0.436 |
| Lactate dehydrogenase (U/L) | ||||
| Day 0 | 369.3 ± 81.2 | 344.6 ± 110.8 | 391.2 ± 100.4 | 0.382 |
| Day 2 | 414.4 ± 90.1 | 384.2 ± 100.6 | 403.5 ± 95.9 | 0.647 |
| Day 7 | 236.8 ± 70.3 | 229.5 ± 90.4 | 231.4 ± 80.7 | 0.961 |