Figure 3.

In vivo transplacental transport of (1-¹³C) valine, (1-¹³C) leucine, (1-¹³C) isoleucine, [Methyl-²H₃] methionine, [U-¹³C₄] threonine, [1-¹³C] phenylalanine, [4,4,5,5-²H₄] lysine, [Ring 2-¹³C] histidine, and [Indole-²H₅] tryptophan. Fetal vein/maternal artery (Fv/M) mole percent excess (MPE) ratios of stable isotope-labeled nine EAAs after intravenous infusion of a mixture of labeled EAAs to the control and MNR pregnant baboon at cesarean section (GD 140). Umbilical vein blood samples were obtained 5 min after the completion of EAA infusion. Fv/M MPE ratios of valine, leucine, isoleucine, methionine, threonine, phenylalanine, lysine, histidine, tryptophan in control (n = 8) and MNR (n = 11) baboons at GD 140. Medians ± IQR, * p < 0.05. KS normality test p value: (1-¹³C) valine (Control, p > 0.10; MNR, p > 0.10; passed normality), (1-¹³C) leucine (Control, p > 0.10; MNR, p > 0.10; passed normality), (1-¹³C) isoleucine (Control, p > 0.10; MNR, p > 0.10; passed normality), [Methyl-²H₃] methionine (Control, p > 0.10; MNR, p > 0.10; passed normality), [U-¹³C₄] threonine (Control, p = 0.010, did not pass normality; MNR, p > 0.10; passed normality), [1-¹³C] phenylalanine (Control, p > 0.10; MNR, p > 0.10; passed normality), [4,4,5,5-²H₄] lysine (Control, p > 0.10; MNR, p > 0.10; passed normality), [Ring 2-¹³C] histidine (Control, p = 0.04, did not pass normality; MNR, p > 0.10; passed normality), [Indole-²H₅] tryptophan (Control, p = 0.01, did not pass normality; MNR, p > 0.10; passed normality).