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. 2021 Aug 11;11(8):2048. doi: 10.3390/nano11082048

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© 2021 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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Characterization of elliptical Co@Au (Co@Au NEs) nanoparticles after thiol and MTX (SH-MTX) conjugation via Zetasizer and FTIR. (a) Dispersion ability of Co@Au NEs as analyzed by measuring zeta potential at varying pH. (b) Measurement of zeta potential after conjugation of Co@Au NEs with thiol (SH) and Methotrexate (MTX). (c) FTIR analysis of Co@Au NEs, thiol and MTX. (d) FTIR analysis of Co@Au NEs followed by thiol and MTX conjugation, confirming the successful grafting of MTX onto elliptical nanoparticles.