Table 3.
Data on the prevalence of hypermetabolic axillary lymph nodes and deltoid muscle uptake at 2-[18F]FDG PET/CT after COVID-19 vaccine.
| Authors | All Cases Evaluated with 2-[18F]FDG PET/CT after COVID-19 Vaccine | Cases Evaluated with 2-[18F]FDG PET/CT after the First Dose of COVID-19 Vaccine | Cases Evaluated with 2-[18F]FDG PET/CT after the Second Dose of COVID-19 Vaccine | ||||
|---|---|---|---|---|---|---|---|
| HALNs Present | HALNs Absent | Uptake at Injection Site of COVID-19 Vaccine | HALNs Present | HALNs Absent | HALNs Present | HALNs Absent | |
| Adin et al. [10] | 9/68 (13%) |
59/68 (87%) |
8/68 (12%) |
2/41 (5%) |
39/41 (95%) |
7/27 (26%) |
20/27 (74%) |
| Bernstine et al. [11] | 168/650 (26%) |
482/650 (74%) |
52/168 (31%) |
57/394 (14%) |
337/394 (86%) |
111/256 (43%) |
145/256 (57%) |
| Cohen et al. [12] | 332/728 (46%) |
396/728 (54%) |
99/266 (37%) |
126/346 (36%) |
220/346 (64%) |
206/382 (54%) |
176/382 (46%) |
| Cohen et al. [13] | 43/137 (31%) |
94/137 (69%) |
NA | 13/51 (25%) |
38/51 (75%) |
30/86 (35%) |
56/86 (65%) |
| Eifer et al. [14] | 170/377 (45%) |
207/377 (55%) |
98/377 (26%) |
NA | NA | NA | NA |
| Eshet et al. [15] | 49/169 (29%) |
120/169 (71%) |
NA | NA | NA | 49/169 (29%) |
120/169 (71%) |
| Schroeder et al. [16] | 4/54 (7%) |
50/54 (93%) |
8/55 (15%) |
NA | NA | NA | NA |
| Shin et al. [17] | 28/31 (90%) |
3/31 (10%) |
22/30 (73%) |
NA | NA | NA | NA |
| Skawran et al. [18] | 75/140 (54%) |
65/140 (46%) |
NA | 27/48 (56%) |
21/48 (44%) |
48/92 (52%) |
44/92 (48%) |
| Pooled values (95%CI) | 37% (27–47%) |
63% (53–73%) |
30% (20–41%) |
26% (13–42%) |
74% (58–87%) |
41% (32–50%) |
59% (50–68%) |
| Heterogeneity (I2) | High (95%) | High (95%) | High (90%) | High (95%) | High (95%) | High (87%) | High (87%) |
| Egger’s test (publication bias) | p = 0.8 (absent) | p = 0.8 (absent) | p = 0.6 (absent) | p = 0.5 (absent) | p = 0.5 (absent) | p = 0.3 (absent) | p = 0.3 (absent) |
Legend: 2-[18F]FDG = fluorine-18 fluorodeoxyglucose; 95%CI = 95% confidence interval; HALNs = hypermetabolic axillary lymph nodes; NA = not available or calculable; PET/CT = positron emission tomography/computed tomography.