Table 4.
Binding energies obtained from docking experiments of selected major compounds in Gaultheria pumila berries extract, as well as the known inhibitors galantamine and kojic acid over acetylcholinesterase (TcAChE), butyrylcholinesterase, (hBChE) and tyrosinase accordingly.
| Compound | Binding Energy (kcal/mol) Acetylcholinesterase |
Binding Energy (kcal/mol) Butyrylcholinesterase |
Binding Energy (kcal/mol) Tyrosinase |
|---|---|---|---|
| Scupolin I (29) | −10.582 | −7.361 | −4.303 |
| Unedide (2) | −12.081 | −10.972 | −10.643 |
| Nuzhenal B (21) | −15.289 | −11.079 | −10.576 |
| Myricetin O-rhamnoside (14) | −15.175 | −11.581 | −10.528 |
| Luteolin 7-glucuronide (19) | −13.757 | −11.777 | −11.323 |
| Galantamine | −12.989 | −7.125 | - |
| Kojic acid | - | - | −6.050 |