Table 4.
Comparison of the present method with other reported methods for determination of methylene blue and its metabolite residues in aquatic products.
| Extraction Organic Solvent | Purification Agent | Sample | N 1 | LR (µg/L) | LOQ (µg/kg) | RSD (%) | Recovery (%) | Ref. |
|---|---|---|---|---|---|---|---|---|
| Acetonitrile | ALN cartridge | Aquatic products | 4 | 1–500 | 1.0 | 1.05–8.63 | 71.8–97.5 | Present method |
| Acetonitrile containing 0.1% of formic acid | - | Aquatic products | 4 | 0.04–2.0 | 0.4–4 | 5–15 | 87–130 | [18] |
| Ammonium acetate buffer solution and acetonitrile | Liquid–liquid distribution and PRS 2 cartridge | Aquatic products | 4 | 1–100 | 2 | 2.3–13.0 | 70.3–92.1 | [19] |
| Acetonitrile | - | Plasma | 2 | 1–1000 | 30 | 3.6–11.9 | 97.9–108.0 | [20] |
| Acetonitrile | CBA and SCX-SPE 3 cartridges | Eel | 2 | 2–16 | 0.25 | 8.3–14.5 | 84.1–102.1 | [21] |
| Acetonitrile/sodium acetate buffer solution | ALN cartridge | Eel, toasted eel, and shrimp | 1 | 2.0–100.0 | 0.5 | 4.4–16.3 | 73.0–108.3 | [22] |
1 Number of analytes. 2 Propanesulfonic acid bonded. 3 Weak cation exchange cartridges and strong cation exchange cartridges-solid phase extraction.