Table 4.

List of metabolic pathways dysregulated for two comparison sets.

Sr.#	Pathway	Glioma vs. Control				LGG vs. HGG
		Hits	RawP	FDR	Impact	Hits	RawP	FDR	Impact
1	Alanine, aspartate, and glutamate metabolism	06//28	2.13 × 10−6	8.34 × 10−5	0.70754	06//28	4.57 × 10−7	1.92 × 10−5	0.48398
2	D-Glutamine and D-glutamate metabolism	2//6	0.00332	0.03984	0.5	2//6	0.00207	0.01937	0.5
3	Arginine biosynthesis	4//14	4.00 × 10−5	0.00084	0.19289	3//14	0.00052	0.00739	0.19289
4	Glutathione metabolism	3//28	0.00829	0.08708	0.28281	2//28	0.04453	1	0.12939
5	Aminoacyl-tRNA biosynthesis	13//48	8.36 × 10−15	7.02 × 10−13	0.16667	10//48	2.30 × 10−11	1.93 × 10−9	0
6	Glycine, serine, and threonine metabolism	2//33	0.09068	0.40088	0.21707	4//33	0.00053	0.00739	0.24577
7	Arginine and proline metabolism	4//38	0.0023	0.0386	0.20172	5//38	6.13 × 10−5	0.00129	0.25763
8	Phenylalanine, tyrosine, and tryptophan biosynthesis	1//4	0.06057	0.31497	0.5	NA
9	Tryptophan metabolism	1//41	0.47705	1	0.14305	NA
10	Phenylalanine metabolism	1//10	0.14488	0.55316	0.35714	NA