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. 2021 Jul 31;13(8):2670. doi: 10.3390/nu13082670

Table 2.

General characteristics of the mothers and corresponding breast milk OPN (Osteopontin) levels.

General Characteristics n (%) OPN, mg/L
(Mean ± SD)
p 1 p 2
n 85 (100.0) 137.1 ± 56.8
Age groups
19–24 years 20 (23.5) 137.8 ± 65.8 - 0.334
25–29 years 22 (25.9) 141.4 ± 53.8
30–34 years 17 (20.0) 153.6 ± 49.3
35–39 years 26 (30.6) 121.9 ± 55.9
Age, mean± sd 30.2 ± 6.0
Birth method
Cervical vaginal route 52 (61.2) 160.6 ± 48.8 <0.001 ** -
Cesarean section 33 (38.8) 99.9 ± 48.5
BMI (kg/m2) classification
Pre-pregnancy
<18.5 (underweight) 5 (5.9) 140.6 ± 37.9 - 0.108
18.5–24.9 (optimal) 51 (60.0) 143.6 ± 53.6
25.0–29.9 (overweight) 21 (24.7) 111.9 ± 56.8
≥30 (obese) 8 (9.4) 159.1 ± 73.5
BMI, mean ± sd 23.6 ± 3.3
Postpartum/Lactation (3rd month)
<18.5 (underweight) - - - <0.001 **
18.5–24.9 (optimal) 39 (45.9) 156.4 ± 46.2 a
25.0–29.9 (overweight) 31 (36.5) 140.8 ± 61.2 a
≥30 (obese) 15 (17.6) 78.9 ± 28.8 b
BMI, mean± sd 25.8 ± 3.8
Weight gain during pregnancy
Insufficient 20 (23.5) 158.2 ± 40.3 a - 0.020 *
Adequate 24 (28.) 149.0 ± 60.4 a
Excessive 41 (48.2) 119.8 ± 57.4 b
Smoking status
Pre-pregnancy
Yes 34 (40.0) 102.0 ± 41.4 <0.001 ** -
No 51 (60.0) 160.4 ± 53.8
Pregnancy
Yes 14 (16.5) 103.1 ± 50.6 0.013 * -
No 71 (83.5) 143.8 ± 55.9
Postpartum/Lactation
Yes 13 (15.3) 98.3 ± 49.2 0.007 * -
No 72 (84.7) 144.1 ± 55.5

p1; independent samples t-test, p 2; ANOVA test, * p < 0.05, ** p < 0.001. a,b; A statistically significant difference between binary groups is expressed by different lower-case letters (p; independent samples t-test).