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ECM components: Interstitial matrix consists of fibrillar collagen, elastin, proteoglycans and glycoproteins, basement membrane is made of non-fibrillar collagen and laminin. Cardiomyocytes attach to the basement membrane via transmembrane proteins such as integrin and Dystroglycan. The excessive ECM secretion after the infarction leads to tissue hypertrophy and scar formation. The figure of the MI heart was adopted from the Servier Medical Art under the CC BY 3.0 license.
