FIG. 3.
AP-1 and NF-κB transcription activities are not inhibited by dnNFAT. NFAT, AP-1, and NF-κB transcription activities were measured by using luciferase reporter plasmids cotransfected in Jurkat T cells without (Control) and with dnNFAT. Luciferase activity was measured in cultures incubated with ionomycin (2 μM) and PMA (100 nM). The data are presented as relative percentage activity compared to a control without dnNFAT.