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. 2021 Aug 17;14(8):809. doi: 10.3390/ph14080809

Figure 2.

Figure 2

Fold change in insulin secretion as measured by luciferase activity in MIN6 β cells after incubation with tolbutamide (Tolb), chlorpropamide (Chpp), glibenclamide (Gbcd), glipizide (Gpz), glimepiride (Glim), repaglinide (Repa) and glucose (Gluc) (A) and incubation after preincubation with 250 µM diazoxide (DZ) (B). Fold change in insulin secretion as measured by luciferase activity in MIN6 β cells expressing Ins-GLuc normalized to the activity of 0 mM glucose and expressed as the means ± SEM (n ≥ 8). * p < 0.05; *** p < 0.001; **** p < 0.0001.