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. 2021 Aug 6;13(8):1214. doi: 10.3390/pharmaceutics13081214

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© 2021 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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Upper panel shows the scheme of the synthesis of G(4)-PAMAM-FITC (2), Ac-La-G(4)-PAMAM-FITC (4), and Ac-La-G(4)-PAMAM-FITC/sorafenib (5) dendrimers; bottom panel shows representative single confocal slices of fixed HepG-2 cells: HepG-2 cells imaged with (a) DAPI; (b) Phalloidin-TRITC; (c) Ac-La-G(4)-PAMAM-FITC 4; (d) overlay after an incubation period of 15 min. Bar: 25 μm. Adapted with permission [32]. Copyright 2017, Elsevier B.V.