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. 2021 Aug 23;9(8):196. doi: 10.3390/toxics9080196

Table 3.

Hazard quotients derived for amoxicillin, enrofloxacin, and neomycin.

Pharmaceuticals MECmean (µg/L) MECmax (µg/L) Lowest NOEC (mg/L) AF PNEC (µg/L) HQ
Based on MECmean
HQ Based on MECmax
Amoxicillin 0.068 1.654 0.00078 b 10 0.078 0.87 21.2
Enrofloxacin 0.087 30 0.049 c 10 4.9 0.018 6.1
Neomycin 1.18 1.18 a 0.03 d 10 3.0 0.39 0.39

a The same value as MECmean was used because MECmax was not available. b Based on the Synechococcuse leopoliensis 96-h growth NOEC [19]. c Based on the Microcystis aeruginosa 5-d growth EC50 in the literature [44]. d Based on the Daphnia magna 21-d survival NOEC [12].