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Linear diagrams of VP1 and its fragments. (A) Full-length VP1 sequence. VP1 and VP2 differ in that VP1 has an N-terminal extension (VP1u). Additionally, the sequence similarity of a 5-residue motif found in VP1u and VP2 is shown. (B) Histidine-tagged peptides VP1uWT and VP1uAT. MAB-MAB8293 epitope (residues 555–571 of VP1); PLA2-phospholipase A2-like domain; VP1u-VP1 unique region.
