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. 2021 Aug 4;9(8):860. doi: 10.3390/vaccines9080860

Table 2.

Kappa coefficient, sensitivity and specificity of VP1uAT ELISA and VLP IgG ELISA with the neutralization assay as the gold standard.

Qualitative VP1u Results Qualitative VLP IgG Results
Qualitative Neutralization Results Positive Negative Positive Negative
Positive a 40 1 36 5
Negative 0 8 1 7
Kappa coefficient (95% CI) 0.93 (0.79, 1.00) 0.63 (0.36, 0.89)
Sensitivity (95% CI) 97.6% (87.1%, 99.9%) 87.8% (73.8%, 95.9%)
Specificity (95% CI) 100% 87.5% (47.4%, 99.7%)

a Serum samples were obtained from patients 120 days after hospitalization for acute parvovirus B19 infection or from additional patients who were not experiencing aplastic crisis.