Table 1.

Neutralization Titers (IC₅₀) against pseudotyped viruses displaying each spike variant.

	IN-IN (Prime-Boost)			IN-IM (Prime-Boost)
	Wuhan	Alpha Variant	Neutralization Activity (%) (Alpha/Wuhan)	Wuhan	Alpha Variant	Neutralization Activity (%) (Alpha/Wuhan)
#1	2801.50	2528.20	90.24	1754.7	1381.1	78.70
#2	1199.00	824.39	68.75	2253	1785.3	79.24
#3	1253.40	814.76	65.00	3633.8	2213.5	60.91
#4	561.35	328.49	58.51	522.44	333.29	63.79
#5	464.40	471.03	101.42	407.48	332.19	81.52
	Wuhan	Beta Variant	Neutralization Activity (%) (Beta/Wuhan)	Wuhan	Beta Variant	Neutralization Activity (%) (Beta/Wuhan)
#1	2801.50	1810.80	64.63	1754.7	1289.4	73.48
#2	1199.00	331.83	27.67	2253	2706.7	120.13
#3	1253.40	2226.50	177.63	3633.8	3181.6	87.55
#4	561.35	0.70	0.12	522.44	284.15	54.38
#5	464.40	190.63	41.04	407.48	343.41	84.27
	Wuhan	Gamma Variant	Neutralization Activity (%) (Gamma/Wuhan)	Wuhan	Gamma Variant	Neutralization Activity (%) (Gamma/Wuhan)
#1	2801.50	1949.00	69.56	1754.7	1613.4	91.94
#2	1199.00	561.39	46.82	2253	2138.3	94.90
#3	1253.40	1814.10	144.73	3633.8	3782.7	104.09
#4	561.35	18.52	3.29	522.44	248.49	47.56
#5	464.40	157.43	33.89	407.48	336.46	82.57