Table 4.
Results of univariate and multivariate logistic regression model for tissues with polyps or adenomas (PA) of colon-rectum compared to healthy tissues (controls). Univariate odds ratios are also shown for all factors with univariate association within 10% tolerance (p-value < 0.1) that were included in the multivariate model and for all bacterial toxins.
| Univariate | Multivariate | |||||
|---|---|---|---|---|---|---|
| Characteristic | OR 1 | 95%CI 1 | p-Value 1 | OR 1 | 95%CI 1 | p-Value 1 |
| cif, yes vs. no | 2.53 | 1.06, 6.14 | 0.036 | 2.57 | 1.06, 6.33 | 0.037 |
| cdt, yes vs. no | 1.94 | 0.90, 4.10 | 0.085 | |||
| cnf1, yes vs. no | 1.20 | 0.59, 2.35 | 0.61 | |||
| pks+, yes vs. no | 1.37 | 0.72, 2.60 | 0.33 | |||
| bft, yes vs. no | 0.74 | 0.26, 1.82 | 0.54 | |||
| Polygenic Risk Score (PRS) | 1.36 | 1.00, 1.87 | 0.051 | |||
| Sex, F vs. M | 0.49 | 0.28, 0.85 | 0.011 | 0.48 | 0.27, 0.84 | 0.011 |
| BMI | 1.07 | 1.00, 1.15 | 0.068 | |||
| Wine consumption, yes vs. no | 1.58 | 0.92, 2.74 | 0.10 | |||
1 OR, odds ratio; CI, confidence interval; in bold, p-value < 0.05.