Table 5.
Results of univariate and multivariate logistic regression model for tissues with hyperplastic polyps (HP) of colon-rectum compared to healthy tissues (controls). Univariate odds ratios are also shown for all factors with univariate association within 10% tolerance (p-value < 0.1) that were included in the multivariate model and for all bacterial toxins.
| Univariate | Multivariate | |||||
|---|---|---|---|---|---|---|
| Characteristic | OR 1 | 95%CI 1 | p-Value 1 | OR1 | 95%CI 1 | p-Value 1 |
| cif, yes vs. no | 2.04 | 0.71, 5.49 | 0.17 | |||
| cdt, yes vs. no | 0.30 | 0.05, 1.11 | 0.12 | |||
| cnf1, yes vs. no | 1.20 | 0.59, 2.35 | 0.61 | |||
| pks+, yes vs. no | 1.37 | 0.72, 2.60 | 0.33 | |||
| bft, yes vs. no | 0.74 | 0.26, 1.82 | 0.54 | |||
| Sex, F vs. M | 0.42 | 0.22, 0.79 | 0.007 | |||
| BMI | 1.08 | 1.00, 1.16 | 0.047 | 1.10 | 1.01, 1.19 | 0.026 |
| Alcohol consumption, yes vs. no | 2.07 | 1.06, 4.02 | 0.032 | |||
| Non-drinker, yes vs. no | 0.25 | 0.06, 0.74 | 0.027 | 0.23 | 0.05, 0.73 | 0.026 |
| Smoking | ||||||
| Yes vs. no | 2.81 | 1.31, 6.13 | 0.008 | |||
| Ex vs. no | 1.54 | 0.73, 3.24 | 0.25 | |||
| Smoking, yes vs. no | 2.01 | 1.07, 3.88 | 0.034 | |||
| Previous removal of polyps | ||||||
| Yes benign vs. yes malignant | 5.79 | 2.10, 18.9 | 0.001 | 5.45 | 1.90, 18.3 | 0.003 |
| No vs. yes malignant | 1.31 | 0.49, 4.16 | 0.62 | 1.17 | 0.42, 3.81 | 0.78 |
1 OR, odds ratio; CI, confidence interval; in bold, p-value < 0.05.