Table 4.

Overview of the different involvement of the USUV-antigen in cell types in different organs.

Organ	Tissue/Cell	Immunolabeling *
All organs	Endothelial cells Vascular wall Mononucleated cells Intravascular leukocytes	+++ ++ ++ +
Liver	Kupffer’s cells Hepatocytes	+++ +
Spleen	Capsular stromal cells High walled veins	++ +
Heart	Cardiomyocytes Endocardium	+++ ++
Lung	Type I pneumocytes	+
Air sacs	Spindle stromal cells	+
Kidney	Tubular epithelium Glomeruli	+++ +
Skin	Keratinocytes Feathers	+ ++
Cerebrum	Neurons Glial cells	+++ +
Cerebellum	Neurons Glial cells	+++ +
Proventriculus	Mucosal epithelium Smooth muscle cells Peripheral ganglion	++ + +
Gizzard	Mucosal epithelium Smooth muscle cells Peripheral ganglion	++ + +
Intestine	Mucosal epithelium Smooth muscle cells Peripheral ganglion	++ + +
Gonads	Sertoli cells Ovary follicular epithelium Germinal cells	+ + +
Thyroid	Follicular epithelium	++
Skeletal muscle	Stromal cells	+

* + few cells infected; ++ moderate numbers of cells infected; +++ numerous cells infected.