Figure 3.

Alignment of the amino acid sequences of residues 690–738 of pestivirus glycoprotein E2. The positions of amino acid residues are numbered based on those of CSFV strain TD/96/TWN. Sequences are clustered based on their allocation to genotypes as in Table 1. For each virus strain the genotype and the accession number are indicated. The key residues which might be responsible for the reactivity patterns of the mAbs characterized in this study are boxed and highlighted with different colors. The residues P709, L709, E713, G725, V738 and I738 are highlighted with light blue, pink, blue, green, orange and red, respectively. Cysteine residues are indicated by an asterisk above the alignment.